Prevalence of antibiotic resistance among patients with Escherichia coli urinary tract infection in a private hospital at Lahore-Pakistan

Of 127 urine isolates from patients at national hospital and medical center 93 were positive for escherichia coli (e.coli). out of these 93 isolates,73%,77%,82% & 71% were resistant to fluoroquinolones,trimethoprim-sulfamethoxazole (sxt),ampicillin-sulbactam & ceftriaxone respectively. resistance to nitofurontoin,fosfomycin,pipericillin-tazobactam,cefoperazone-sulbactam & carbapenems (imipenem-cilastatin,meropenem) was found to be only 14%,8.7%,4.4%,1.4% & 1.1% respectively. for uncomplicated urinary tract infection (uti) empiric antibiotics should include nitofurontoin and fosfomycin. for severe and complicated infection parenteral antimicrobial with least resistance should be used.