Comparison between pioglitazone and metformin in terms of efficacy in patients with polycystic ovarian syndrome

Aim: to compare the efficacy ofpioglitazone and metforminin women with polycystic ovary syndrome. methods: this randomized trial was conducted at department of obstetrics & gynecology,bahawal victoria hospital,bahawalpur from june 2015 to december 2015. total 70 patients with polycystic ovary syndrome having 20-40 years of age with duration of disease >3 month were recruited. results: the mean age of women in group a was 29.97±5.28 years and in group b was 30.37±5.63 years. mean duration of marriage in study group a was 4.74±2.40 years and in study group b was 4.91± 2.25 years. the mean duration of disease in study group a was 3.69±1.59 years and in study group b was 3.94±1.84 years. efficacy of group a (metformin group) was 19(54.29%) while in group b (pioglitazone group) was 29(82.86%) with p-value = 0.010. conclusion: this study concluded that pioglitazone is more effective as compare to metformin for ovulation induction in women with polycystic ovary syndrome.