To calculate the frequency of post-transfusion lung injury in neonates

Background: transfusion related acute lung injury (trali) is a serious blood transfusion complications characterized by the acute onset of non-cardiogenic pulmonary edema following transfusion of blood products. it is defined as an acute lung injury that is temporally related to a blood transfusion; specifically,it occurs within the first six hours following a transfusion. aim: to calculate the frequency of post transfusion lung injury in neonates settings: neonatal icu and hdu in department of pediatrics,of services hospital lahore study design: descriptive study (case series) methodology: after informed consent 320 neonates were included in study. informed consent was taken from parents. data of neonates who received blood transfusion was noted on a predesigned performa (attached) and following information was noted gestational age,birth weight,age,gender,volume transfused,indication of transfusion,before transfusion respiratory rate and oxygen saturation was noted and changes in these parameters were recorded at 30 minutes interval for 6 hours and x ray was performed after 6 hours. results: in our study,out of 320 cases,201(62.81%) were between 1-15 days while 119(37.19%) were between 16-28 days of life,mean±sd was calculated as 13.58±7.59 days,187(58.44%) were male and 133(41.56%) were female,frequency of post transfusion lung injury in neonates was recorded as 44(13.75%) while 276(86.25%) had no findings of the morbidity. conclusion: we concluded that the frequency of post transfusion lung injury is higher among neonates but the results of our study are primary and needs some other studies to validate our findings. © 2016,lahore medical and dental college. all rights reserved.