Role of optical coherence tomography in early diagnosis of open angle glaucoma: An experience

Objective: to evaluate role of cirrus high definition optical coherence tomography (hd-oct) in early diagnosis of glaucoma by measuring optic nerve head (onh),retinal nerve fiber layer (rnfl) and ganglion cell complex (gcc) analysis. subjects & methods: the cross sectional study was conducted at ch. rehmat ali hospital lahore from march 2014 to september 2015. a total 115 patients were enrolled in study,comprises two groups; a) diagnosed glaucoma patients and b) glaucoma suspect (pre perimetric glaucoma) second group further divided in 1) ocular hypertension 2) enlarged physiological cup. all patients underwent comprehensive ophthalmic exam,bcva,iop,using goldman applanation tonometer. anterior segment examination on slit lamp,gonioscopy and oct on cirrus hd-oct spectralis machine. results: out of 115 patients 65 (56%) were male,50 (44%) were female. mean age 43.7(sd±10.3) years. on oct analysis patients with glaucoma and ocular hypertension shows superior as well as inferior hemisphere defects 63.33% and 36.66% respectively. while 80% showed gcc defects. ocular hypertensive 56% (14 eyes) showed rnfl defects,20% show gcc deviation. patients with enlarged cup show 26.66% changes in rnfl,while 13.33% shows gcc changes. conclusion: sd-oct of optic nerve head onh,retinal nerve fiber layer rnfl,and macula gcc has a role in early diagnosis and monitoring progression of glaucoma. © 2016,lahore medical and dental college. all rights reserved.