Histology of Rabbit's Testes as Influenced by Municipal Waste Water

Relative effect of different concentrations of municipal wastewater i.e.,(1) tape water (control),(2) 50% concentration of municipal wastewater and (3) 100% concentration of municipal wastewater on histology of rabbit's testes was studied at the animal house of gomal medical college,dera ismail khan during the year 2013-14. the study was laid out in randomized control trail (rct). sixty male rabbits classified into three groups a,b and c and each group further subdivided into two subgroups viz.,a1,a2,b1,b2,c1 and c2 respectively. group a1,b1,c1 was treated for 30 days whereas group a2,b2,c2 was treated for 60 days with tape water,50% and 100& concentrations of municipal wastewater respectively. data was recorded on various morphological and microscopic parameters viz; degenerative cells in the lumen,sertoli cells count,leydig cells/hpf,cell count/tubule,degenerative changes in epithelium and vacuolization. results revealed highly significant (p≤ 0.01) differences among various concentrations of municipal wastewater for all the studied traits in comparison to control (tape water) whereas the duration of treatments were found to be statistically at par with each other. maximum cell counts/tubule,leydig cells count and sertoli cells count was recorded in control and decreased steeply with an increase in municipal wastewater concentration. similarly maximum degenerative changes in epithelium,degenerative changes in lumen and intraepithelial vacuolization were observed in 100% concentration of municipal wastewater. the instant results suggest that municipal wastewater adversely affects the testicular histology.