Frequency of pregnancy following laparoscopic ovarian drilling in patients with Clomiphene resistant polycystic ovarian syndrome

Aim: to study was to determine the frequency of pregnancy following laparoscopic ovarian drilling in our patients with clomiphene citrate resistant polycystic ovarian syndrome. methods: this case series study was carried out in the department of obstetrics and gynaecology,nishtar hospital,multan from january 2014 to december 2014. a total of 100 patients with clomiphene citrate resistant polycystic ovarian syndrome were included in the study. results: total 5327 patients visited gynaecology opd during six month study period. overall frequency of pcos was 4.84% and among infertility cases frequency was 26.93%. majority of cases of pcos were in age group 20-30 years. out of 258 cases of pcos,72% of cases were having primary infertility and 28% were having secondary infertility. 41.86% of cases were resistant to cc in a dose of 150 mg for three cycles. conception rate was 66% in 6month follow up period after lod. conclusion: lod is a safe and cost effective procedure. a single treatment results in uni-follicular ovulation. no need of continuous monitoring as seen with hormonal treatment. no fear of multiple births and ovarian hyper stimulation. correction of hormonal levels prevents miscarriages. lod increase the sensitivity to gonadotrophins. and it is as effective as gonadotrophins in pcos.