Frequency of patients with Abnormal Celiac Serological Marker (Anti-Tissue Transglutaminase IGA) in newly diagnosed cases of diabetes mellitus-I without gastrointestinal tract symptoms

Aim: to determine the frequency of patients with abnormal celiac serological marker (anti-tissue transglutaminase iga) in newly diagnosed cases of type i diabetes mellitus without gastrointestinal tract symptoms. methods: this cross sectional study was conducted at department of pediatric medicine,sahiwal medical college,sahiwal from september 2015 to august 2016. total 100 newly diagnosed cases at the time of admission in this unit with type i diabetes mellitus without git symptoms (loose motions with or without vomiting),either male or female having age from 6-16 years were selected. results: mean age of the children was 10.66±3.55. out of 100 diabetic children,abnormal celiac serological marker was found in 20 (20%) children. abnormal celiac serological marker was noted in 12(20.34%) children and 8(19.51%) children respectively in age group 6-11 year and 12-16 years. abnormal celiac serological marker was found in 8 (21.62%) male and 12(19.05%) female children. conclusion: results of this study showed a high percentage of abnormal celiac serological marker. insignificant association of abnormal celiac serological marker with age,gender and family history of diabetes mellitus was noted.