Frequency of acute blood transfusion reactions encountered in patients in a tertiary care hospital

Aim: to report acute transfusion reactions occurring in patients receiving transfusion of whole blood/components in a tertiary care hospital. methods: a total number of 250 patients who received transfusion of blood components from april 2016 to dec 2016 were selected for analysis. all transfusion reactions were diagnosed clinically as well as by laboratory findings. complete blood count,culture sensitivity and specificity,and urine analysis was done in all clinically suspected patients of acute transfusion reactions. arts were further classified into different subtypes. results: in this study,the mean age of participants was 41.76±11.06 years. there were 113(43.5%) female patients and 147(56.5%) male patients. regarding type of transfusion,most of the patients 111(42.7%) received whole blood transfusion,96(36.9%) received packed red cells. blood transfusion reactions occurred in 7(2.7%) patients,out of which 4 reactions occurred in patients who received whole blood transfusion,1 reaction in patients who received platelet concentrates and 2 reactions occurred in patients who received packed red cells. most common types of reactions were febrile non-hemolytic transfusion reactions occurred in 3(1.2%) patients,allergic reactions occurred in 2(0.8%) patients,hemolytic transfusion reaction in 1(0.4%) patients,and bacterial contamination in 1(0.4%) donor blood was detected. conclusion: frequency of blood transfusion reactions in this study was 2.7%. febrile non-hemolytic transfusion reactions and allergic reactions were most common reactions.