Type 2 diabetes and following incidence of breast cancer in a group of diabetic women

Background: diabetes and breast cancer are diagnosed within the same women more often than would be expecting by chance. aim: to evaluate the association between diabetes and incidence of breast cancer in a group of diabetic women. methods: study engaged 50 diabetic women diagnosed with breast cancer. the women ranged in age from 45-55 years old. 20 age matched women with no history of any disease were taken as controls. patients were taken from department of oncology and local breast clinic of lahore city. inclusion criteria was based on the development of breast cancer after diagnosis of type 2 diabetes. duration of study was march,2015 to sep,2015. insulin doses and duration of insulin treatment were recorded. results: age,bmi and level of serum insulin and insulin resistance in diabetic patients with breast cancer are tabulated. it was observed that mean age of patients and normal subject was 46.0 and 45 years. mean bmi of patients was high as compared to the bmi of controls and its showed significant difference (p<0.05). level of blood sugar and serum insulin was high in patients as compared to controls and showed high significant difference (p<0.001). values of insulin resistance were also high of patients as compared to the insulin resistance of controls. conclusion: it is concluded that middle age obese women with poorly controlled diabetes treated with high units of insulin are prone to develop breast cancer.