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To observe the cellular toxicity of carcinogenic compound on lungs of albino rats,an experimental study
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نویسنده
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sharif s. ,umar m. ,khan s.r. ,shuja n.
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منبع
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pakistan journal of medical and health sciences - 2017 - دوره : 11 - شماره : 3 - صفحه:1090 -1091
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چکیده
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The aim of this study was to observe the pulmonary toxicity of hexavalent chromium [cr(vi)]. in the current study albino rats were used as experimental animals and the target organ was lungs. hexavalent chromium [cr(vi)],(5mg/kg b.w) was given orally to the albino rats. a significant (< 0.05) increase of hexavalent chromium was observed in lungs homogenate (7.574±.349ìg/g of wet tissue) of treated rats as compared with the control (0.00±.000 ìg/g of wet tissue) respectively. the current study indicated that hexavalent chromium may cause both cytotoxicity and genotoxicity in a biological system.
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کلیدواژه
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Albino rats; Hexavalent chromium; Pulmonary toxicity
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آدرس
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histopathology,amnainayat medical and dental college,lahore, Pakistan, anatomy nawaz sharif medical college,university of gujrat, Pakistan, biochemistry,university college of medicine and dentistry,university of lahore, Pakistan, biochemistry lahore medical,dental college,lahore, Pakistan
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Authors
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