Association of first trimester threatened miscarriage with preterm prelabor rupture of membrane and preterm delivery

Aim: to determine the association of first trimester threatened miscarriage with preterm premature rupture of membranes and preterm delivery. methods: this study was conducted from april 2016 to april 2017 in alkhidmat teaching mansoorahhospitl. in this cohort study,a total of 200 pregnant women were included,with group a,having history of 1st trimester bleeding and group b,having no history of 1st trimester bleeding,between 20-35 years of age in both groups with any parity,while twin pregnancy,congenital uterine anomaly,large leiomyomata distorting the uterine cavity assessed by usg,history of chronic diabetes or gestational diabetes diagnosed by glucose tolerance test,history of hypertension or diagnosed by bp monitoring of diastolic bp >90 mmhg on two occasions,vaginal spotting and the finding of an open cervix,polyhydramnios and patients with previous history of preterm labour and pprom were excluded from the study. the collected data was entered and analyzed in computer software spss version 12. frequency and percentage was calculated for categorical variables whereas,mean and standard deviation for age. chi square test was applied to see the association between threatened miscarriage in 1st trimester and pprom or preterm labour. a p value of less then 0.05 was taken as significant. results: in this study,most of the patients in both groups were recorded between 20-25 years of age,in group-a,51% and 43% in group-b,38% in group-a and 41% in group-b were between 26-30 years. mean age was 25.78+3.43 years in group-a and 26.42+2.78 years in group b. association of first trimester threatened miscarriage with preterm delivery was compared in both groups which showed 58% in group-a have preterm delivery as compared to 17% in group-b,with significant difference having p value of < 0.05. association of first trimester threatened miscarriage with pprom was also compared in both groups and found a significant difference in both groups,where 19% in group-a and 8% in group-b were having pprom,with a p value of <0.05. conclusion: this study showed that there is an association of first trimester threatened miscarriage with pprom and preterm delivery.