Frequency of aspergillus infection with nasal polyps and proptosis

Aim: to determine the frequency of aspergillus infection in patients with nasal polyps and proptosis. study design: cross sectional survey setting of study: department of ent,ameer-ud-din medical college/pgmi/lgh,lahore duration : six months ( march 2017 to august 2017 ) sample size: 70 patients methods: non probability purposive sampling. all the 70 patients with nasal polyps and proptosis that were included in this study were assessed by clinical examination. they were investigated specifically by computed tomographic scan to see the intraorbital extension of the disease and fungal culture of the tissue after surgery to determine the presence or absence of aspergillus infection. culture reports were collected within seven days following surgery in the indoor department of ent. informed consent for surgery was taken. demographic profile and relevant data was recorded on research tools. data was entered and analyzed with spss version 17. quantitative variable like age was presented by calculating mean and standard deviation. qualitative variables like gender and presence or absence of aspergillus were presented by calculating frequencies and percentages. results: male and female proportion was almost equal with slight female predominance,46% and 54% respectively. mean age was 26.11 with s.d±10.32. on in 45 (64.3%) patients,apergillus species were demonstrated on fungal culture and rest were negative. conclusion: aspergillus specie was found in approximately two third of patients 45(64.3%) out of 70 patients with nasal polyps and proptosis. so a strong clinical diagnosis of aspergillus rhinosinusitis can be made in patients presenting with nasal polyps with proptosis.