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Towards point-of-care diagnostic and staging tools for human African trypanosomiaisis
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نویسنده
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matovu e. ,kazibwe a.j. ,mugasa c.m. ,ndungu j.m. ,njiru z.k.
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منبع
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journal of tropical medicine - 2012 - شماره : 0
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چکیده
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Human african trypanosomiasis is a debilitating disease prevalent in rural sub-saharan africa. control of this disease almost exclusively relies on chemotherapy that should be driven by accurate diagnosis,given the unacceptable toxicity of the few available drugs. unfortunately,the available diagnostics are characterised by low sensitivities due to the inherent low parasitaemia in natural infections. demonstration of the trypanosomes in body fluids,which is a prerequisite before treatment,often follows complex algorithms. in this paper,we review the available diagnostics and explore recent advances towards development of novel point-of-care diagnostic tests. copyright 2012 enock matovu et al.
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آدرس
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school of veterinary medicine,makerere university,p.o. box 7062, Uganda, school of veterinary medicine,makerere university,p.o. box 7062, Uganda, school of veterinary medicine,makerere university,p.o. box 7062, Uganda, foundation for innovative new diagnostics,budé 16 avenue,1202, Switzerland, school of veterinary sciences,university of queensland,gatton campus,brisbane, Australia
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Authors
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