Correlation of clinicohaematological parameters in paediatric dengue: A retrospective study

Dengue is one of the arthropod-borne (arbo) viral diseases transmitted by female mosquito aedes aegypti. dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality. this was a retrospective study conducted in a tertiary care hospital in coastal karnataka,south india,to know the correlation between the clinical presentation and haematological parameters in the paediatric cases presented with dengue symptoms. a total of 163 paediatric cases who presented fever and dengue-like illness were included in the study. of which,69 were confirmed dengue patients. critical analysis showed that there was a significant difference in the haematological parameters like total leucocyte count,percent differential leucocyte count,and platelets count,in the erythrocyte sedimentation rate (p<0.05 to 0.0001). additionally,when compared to nondengue patients,even the liver function and renal function parameters were significantly deranged (p<0.05 to 0.0001). stratification based on ns1,igg,and igm showed significant alterations in the haematological,hepatic,and renal parameters. with respect to the treatment a small percentage of patients,that is,8% (4 patients),required platelet transfusion as their counts went below 20,000/l. two patients succumbed to their illness while three required icu stay. © 2015 ramakrishna pai jakribettu et al.