journal of toxicology سال:2012 - دوره:2012

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journal of toxicology
سال:2012 - دوره:2012 - شماره:0

A lipocalin-derived peptide modulating fibroblasts and extracellular matrix proteins An in silico approach for evaluating a fraction-based,risk assessment method for total petroleum hydrocarbon mixtures Application of neurochemical markers for assessing health effects after developmental methylmercury and PCB coexposure Application of physiologically based pharmacokinetic models in chemical risk assessment Application of purified botulinum type A neurotoxin to treat experimental trigeminal neuropathy in rats and patients with urinary incontinence and prostatic hyperplasia Are cosmetics used in developing countries safe? use and dermal irritation of body care products in Jimma town,southwestern Ethiopia Bayesian analysis of a lipid-based physiologically based toxicokinetic model for a mixture of PCBs in rats Caspase-10 is the key initiator caspase involved in tributyltin-mediated apoptosis in human immune cells Clostridial spores for cancer therapy: Targeting solid tumour microenvironment Cutting edge PBPK models and analyses: Providing the basis for future modeling efforts and bridges to emerging toxicology paradigms Cypermethrin-induced toxic effect on glycogen metabolism in estuarine clam,Marcia opima (Gmelin,1791) of Ratnagiri coast,Maharashtra Development of screening tools for the interpretation of chemical biomonitoring data Drug-induced oxidative stress and toxicity Effects of exposure to semiconductor nanoparticles on aquatic organisms Evaluation of genotoxic and cytotoxic effects in human peripheral blood lymphocytes exposed in vitro to neonicotinoid insecticides news Function of serum complement in drinking water arsenic toxicity Genetic variations of glutathione S-transferase influence on blood cadmium concentration In vivo toxicity of silver nanoparticles and silver ions in zebrafish (Danio rerio) Integrated use of biomarkers (O:N ratio and acetylcholinesterase inhibition) on Aulacomya ater (Molina,1782) (Bivalvia: Mytilidae) as a criteria for effects of organophosphate pesticide exposition Ion channel-target toxicology Ion channels and zinc: Mechanisms of neurotoxicity and neurodegeneration Kinetic and reaction pathway analysis in the application of botulinum toxin A for wound healing Measured copper toxicity to Cnesterodon decemmaculatus (Pisces: Poeciliidae) and predicted by biotic ligand model in pilcomayo river water: A step for a cross-fish-species extrapolation Measurement of redox potential in nanoecotoxicological investigations Medical applications of clostridia and clostridial toxins Metal toxicity at the synapse: Presynaptic,postsynaptic,and long-term effects Metals and disease MicroRnas in neurotoxicity Mining the virgin land of neurotoxicology: A novel paradigm of neurotoxic peptides action on glycosylated voltage-gated sodium channels Modeling the human kinetic adjustment factor for inhaled volatile organic chemicals: Whole population approach versus distinct subpopulation approach Nanoaerosols including radon decay products in outdoor and indoor air at a suburban site Nervous system of Periplaneta americana cockroach as a model in toxinological studies: A short historical and actual view Neurodegeneration in Alzheimer disease: Role of amyloid precursor protein and presenilin 1 intracellular signaling Nicotine contents in some commonly used toothpastes and toothpowders: A present scenario Nutritional manipulation of one-carbon metabolism: Effects on arsenic methylation and toxicity Occurrence of toxic cyanobacterial blooms in Rio de la Plata Estuary,Argentina: Field study and data analysis Oxidative stress and the ER stress response in a murine model for early-stage alcoholic liver disease Phospholipogenic pharmaceuticals are associated with a higher incidence of histological findings than nonphospholipogenic pharmaceuticals in preclinical toxicology studies Physiologically based pharmacokinetic (PBPK) modeling of metabolic pathways of bromochloromethane in rats Physiologically based toxicokinetic modelling as a tool to support risk assessment: Three case studies Potassium channels blockers from the venom of Androctonus mauretanicus mauretanicus Protective effect of scutellaria litwinowii extract on serum/glucose- deprived cultured PC12 cells and determining the role of reactive oxygen species Quantitative property-property relationship for screening-level prediction of intrinsic clearance of volatile organic chemicals in rats and its integration within PBPK models to predict inhalation pharmacokinetics in humans Reconstructing organophosphorus pesticide doses using the reversed dosimetry approach in a simple physiologically-based pharmacokinetic model Reconstruction of exposure to m-xylene from human biomonitoring data using PBPK modelling,bayesian inference,and Markov chain Monte Carlo simulation Retargeting Clostridium difficile toxin B to neuronal cells as a potential vehicle for cytosolic delivery of therapeutic biomolecules to treat botulism Safety assessment of Zigbir®: A polyherbal formulation in sprague-dawley rats Short communication: Is ethanol-based hand sanitizer involved in acute pancreatitis after excessive disinfection?-An evaluation with the use of PBPK model Specific conditions for resveratrol neuroprotection against ethanol-induced toxicity State of the science: Biologically based modeling in risk assessment Subchronic hepatotoxicity evaluation of 2,3,4,6-tetrachlorophenol in Sprague Dawley rats The Association between chronic arsenic exposure and hypertension: A meta-analysis The adverse effects of air pollution on the nervous system The redox system in C. elegans,a phylogenetic approach Therapeutic use of botulinum toxin in neurorehabilitation Thimerosal-derived ethylmercury is a mitochondrial toxin in human astrocytes: Possible role of fenton chemistry in the oxidation and breakage of mtDNA Towards therapeutic applications of arthropod venom K+-channel blockers in CNS neurologic diseases involving memory acquisition and storage Toxicity of organometal(loids) Update on a pharmacokinetic-centric Alternative Tier II program for MMT-part II: Physiologically based pharmacokinetic modeling and manganese risk assessment Update on a pharmacokinetic-centric alternative tier II program for MMT-Part I: Program implementation and lessons learned Use of Clostridium perfringens enterotoxin and the enterotoxin receptor-binding domain (C-CPE) for cancer treatment: Opportunities and challenges