The relationship of ceruloplasmin and neural tube defects [Seruloplasmin ve nöral tüp defektleri arasi{dotless}ndaki ilişki]

Objective: to compare the levels of ceruloplasmin (cp) in the amniotic fluids and maternal bloods of second trimester fetuses with and without neural tube defects (ntd). materials and methods: 66 pregnant women were included in the study. amniocentesis was performed in 32 women in a patient group diagnosed as ntd or anencephaly and 34 pregnants in a control group with positive down syndrome screening test. maternal bloods were also taken. cp was measured with erel's ceruloplasmin measurement method. results: the cp levels of the amniotic fluid of patients and controls were not statistically different (p>0.05). the cp levels of the maternal bloods were not different in two groups (p>0.05). conclusion: as an antioxidant,no relation was found between cp and ntd.