Comparison of serum androgens and endometrial thickness in obese and non-obese postmenopausal women [Obez ve obez olmayan postmenopozal hastalarda serum androjen seviyeleri ve endometrial kali{dotless}nli{dotless}ǧn karşi{dotless}laşti{dotless}nlmasi{dotless}]

Objective: in this study,we investigated whether serum androgen levels and endometrial thickness differed in obese and non-obese women. material and methods: thirtytwo non-obese (bmi <30) and 48 obese (bmi ≥ 30) women were enrolled. blood samples were analyzed for testosterone,free testosterone,androstenedione,dheas,and shbg,and transvaginal ultrasonography was performed. results: obese women had significantly higher free testosterone and endometrial thickness and significantly lower shbg. eight of 17 women with endometrial thickness >5 mm had significant pathology. conclusion: these results suggest that obesity may be a risk factor for endometrial carcinoma and other pathologies in post-menopausal women through an action on androgen concentrations.