Influence of cumulus cell coculture and cumulus-aided embryo transfer on embryonic development and pregnancy rates [Kumulus hücre kokültürünün ve kumulus destekli embryo transferinin embryonic gelişim ve gebelik oranlari{dotless}na etkisi]

Objective: in this study,we aimed to evaluate the influence of autologous cumulus oocyte complex (coc) coculture on embryonic development and quality,and investigate the implantation and pregnancy rates after cumulus-aided embryo transfer in the icsi-et cycles. material and methods: ninety five consecutive infertile women undergoing their first cycle of ivf teratment were included in the study. the cases were divided into two groups. group 1 consisted of 48 women undergoing icsi,along with autologous cumulus embryo coculture and cumulus-aided emryo transfer. group 2 comprised 47 consecutive patients who consented to undergo icsi and in whom autologous cumulus embryo coculture and cumulus-aided embryo transfer were not performed. implantation and pregnancy rates were compared between the two groups. results: the demographic data and controlled ovarian hyperstimulation parameters were similar in the two groups. the fertilization and cleavage rates were found to be higher in group 1 when compared with group 2 (p=0.03 and 0.001,respectively). there were no statistical significant differences for the implantation and clinical pregnancy rates between the two groups. conclusion: usage of autologous cocs as coculture may improve fertilization and cleavage rates. however,cumulus-aided embryo transfer does not produce an increase in implantation and pregnancy rates.