C-reactive protein and lipoprotein-a as markers of coronary heart disease in polycystic ovary syndrome [Polikistik over sendromlu hastalarda koroner kalp hastali{dotless}klari{dotless}ni{dotless}n belirteci olarak c-reaktif protein ve lipoprotein-a baki{dotless}lmasi{dotless}]

Objective: the aim of this study was to investigate the risk factors of coronary heart disease,crp and lipoprotein-a in polycystic ovary syndrome patients. material and methods: prospectively collected data of polycystic ovary syndrome patients (n=62) and control group (n=40) were compared. results: pcos patients had higher homa-ir,crp,dheas,free testosterone,fai,lh and prolactin levels when compared to the control group. lipoprotein-a levels did not differ between the groups. the obese pcos group had statistically significantly higher fasting blood glucose,total cholesterol,triglyceride,free testosterone,insulin,crp and homa-ir and statistically significantly lower hdl and shbg when compared to normal weight pcos persons. fasting blood glucose,total cholesterol,ldl,shbg,crp,lipoprotein-a,fsh,lh,tsh,dheas and prolactin levels did not differ between the normal weight and obese control groups. conclusion: crp levels increase in polycystic ovary syndrome patients and can be used as a marker of coronary heart disease. future studies can be directed at treatments to decrease crp levels,including antiinflammatory treatments. ©copyright 2012 by the turkish-german gynecological education and research foundation.