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   A new biological marker candidate in female reproductive system diseases: Matrix metalloproteinase with thrombospondin motifs (ADAMTS)  
   
نویسنده demircan k. ,cömertoğlu i. ,akyol s. ,yiğitoğlu b.n. ,sarıkaya e.
منبع journal of the turkish german gynecology association - 2014 - دوره : 15 - شماره : 4 - صفحه:250 -255
چکیده    Playing a key role in the pathophysiology of many diseases,a disintegrin-like and metalloproteinase with thrombospondin type-1 motif (adamts) proteinases have been attracted more attention in obstetrics and gynecology. first discovered in 1997,this zinc-dependent proteinase family has 19 members today. these enzymes,which are located in the extracellular matrix (ecm),have a lot of very important functions,like matrix formation and resorption,angiogenesis,ovulation,and coagulation. in addition,in the pathogenesis of cancer,inflammation,arthritis,and connective tissue diseases,adamts proteinases have crucial roles. the purpose of this review is to collect previous studies about obstetrics and gynecology that are related to adamts enzymes and discuss the subject in many aspects to give an idea to the investigators who are interested in the subject. (j turk ger gynecol assoc 2014; 15: 250-5) © 2014 by the turkish-german gynecological education and research foundation.
کلیدواژه ADAMTS; Biological marker; Reproductive diseases
آدرس department of medical biology,turgut özal university, Turkey, department of medical biology,turgut özal university, Turkey, department of medical biology,turgut özal university, Turkey, department of medical biology,turgut özal university, Turkey, department of reproductive endocrinology,zekai tahir burak women’s health education and research hospital,ankara,turkey,department of obstetrics and gynecology,yıldırım beyazıt university, Turkey
 
     
   
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