USE OF ALUMINOSILICATES SUCH AS ACID - ACTIVATED CLAYS AS SOLID CATALYSTS FOR THE REACTIVITY OF THE VARIOUS CARBONYL COMPOUNDS IN HETEROCYCLIC SYNTHESIS

The heterocyclic compounds, in particular the heterocycles containing five, six and seven members, are the the most abundant of which are an incredibly diverse and large class of ubiquitous molecules that occur in a variety of synthetic drugs, bioactive natural products, pharmaceuticals and agrochemicals. due to the glorious past and impressive present of biologically active heterocyclic scaffolding, these skeletons have long been the subject of immense interest. therefore, substantial efforts have been made development of new and innovative synthesis strategies for the synthesis of these heterocycles involving use of different metallic catalysts, organic and inorganic reagents, etc. among the different types of metals catalysts used, iron-based catalysts are among the cheapest and most readily available. in recent times, several new an innovative synthesis catalyzed by catalysts based on aluminosilicates, heterocycles of diversity at the forefront of the literature by the scientific community. this review highlights advances produced up to now by solid catalysts based on aluminosilicates such as clays activated by acids, zeolites, montomorillonite k10 ... for the synthesis of different assemblies of small heterocycles covering these last years.