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COMPARATIVE STUDY OF ANTIBACTERIAL ACTIVITY OF SOME BIHETEROCYCLIC “TRIAZOLIC-TETRAZOLIC” α-AMINO ACIDDERIVATIVES AGAINSTBACTERIAL STRAINS
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نویسنده
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dioukhane k. ,moussaid s. ,achamlale s. ,alami a. ,kabbour m.r. ,aouine y. ,faraj h. ,bouksaim m. ,gaye m.l.
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منبع
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journal marocain de chimie hétérocyclique - 2020 - دوره : 19 - شماره : 2 - صفحه:87 -91
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چکیده
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The antibacterial activity of a series of some linked 2,5-disubstituted tetrazole-1,2,3-triazole compounds(1a-3a) and (1b-3b) against gram-positive bacterial strains (bacillus subtilis cip 5262, and staphylococcus aureus atcc 25923), and gram-negative (pseudomonas aeruginosaatcc 27853, and salmonellaenteric cip 8039) has been investigated. we used to prove the inhibitory efficacy of these compounds the minimum inhibitory concentration (mic) method.the obtained results proved their effectiveness against the proliferation of certain pathogenic microorganisms, and they made it possible to highlight a very important property concerning the stereochemistry, and the effects of the aryl substituents (methoxy (och3), methyl (ch3), and hydroxyl (oh)).
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کلیدواژه
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Antibacterial activity; Tetrazole; Triazole
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آدرس
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sidi mohamed ben abdellah university, center of doctoral studies “sciences and technology”, faculty of sciences dhar mahraz, faculty of sciences, engineering laboratory of organometallic, molecular materials and environment (limome), Morocco. university cheikh anta diop of dakar, faculty of sciences and techniques, laboratory of chemistry of organic coordination, Senegal, institut national de la recherche agronomique (inra), crra, food quality and technology laboratory, Morocco, cedar rapids medical education foundation (crmef), laboratory of scientific research and pedagogic development (lsrpd), Morocco, sidi mohammed ben abdellah university, faculty of sciences, engineering laboratory of organometallic, molecular materials and environment (limome), Morocco, institut national de la recherche agronomique (inra), crra, food quality and technology laboratory, Morocco, ibn zohr university, faculty of sciences, department of chemistry, Morocco, sidi mohammed ben abdellah university, faculty of sciences, engineering laboratory of organometallic, molecular materials and environment (limome), Morocco, institut national de la recherche agronomique (inra), crra, food quality and technology laboratory, Morocco, university cheikh anta diop of dakar, faculty of sciences and techniques, laboratory of chemistry of organic coordination, Senegal
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Authors
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