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CRYSTAL STRUCTURE OF NEW ANTI-HIV CANDIDATE: [(4-BROMO-3,5-DIMETHYL-PYRAZOL-1-YL)(4-CHLOROPHENYL)- METHYL]-PROPANEDIOATE
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نویسنده
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meskini i. ,daoudi m. ,kerbal a. ,daran j.-c. ,zouihri hafid ,chohan z. h. ,ben hadda t.
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منبع
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journal marocain de chimie hétérocyclique - 2018 - دوره : 17 - شماره : 2 - صفحه:40 -49
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چکیده
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The titled new functionalized n,o,o- donor ligand, [(4-bromo-3,5-dimethylpyrazol-1-yl)(4-chlorophenyl)-methyl]-propanedioate (4) is prepared in good yield throughcondensation of 4-bromo-3,5-dimethyl pyrazole, with 2-arylidene-malonic acid diethyl esters(3). the structure of compound (4) was determined by spectral (ir, 1h nmr), elementalanalyses and x-ray diffraction data. the molecular conformation shows two possible pocketsready to coordinate with two metal atoms.
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کلیدواژه
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O donor ligand ,b-amino dicarbonyl ,malonate ,Michael reaction
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آدرس
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université sidi mohammed ben abdellah, laboratoire de chimie organique, Morocco, université sidi mohammed ben abdellah, laboratoire de chimie organique, Morocco, université sidi mohammed ben abdellah, laboratoire de chimie organique, Morocco, laboratoire de chimie de coordination, 205 route de narbonne, toulouse cedex, France, centre national pour la recherche scientifique et technique, uatrs, Morocco, bahauddin zakariya university, department of chemistry, Pakistan, université mohammed premier, laboratoire chimie matériaux, Morocco
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Authors
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