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The Clinical Application of Raman Spectroscopy for Breast Cancer Detection
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نویسنده
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gao p. ,han b. ,du y. ,zhao g. ,yu z. ,xu w. ,zheng c. ,fan z.
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منبع
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journal of spectroscopy - 2017 - دوره : 2017 - شماره : 0
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چکیده
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Raman spectroscopy has been widely used as an important clinical tool for real-time in vivo cancer diagnosis. raman information can be obtained from whole organisms and tissues,at the cellular level and at the biomolecular level. the aim of this paper is to review the newest developments of raman spectroscopy in the field of breast cancer diagnosis and treatment. raman spectroscopy can distinguish malignant tissues from noncancerous/normal tissues and can assess tumor margins or sentinel lymph nodes during an operation. at the cellular level,raman spectra can be used to monitor the intracellular processes occurring in blood circulation. at the biomolecular level,surface-enhanced raman spectroscopy techniques may help detect the biomarker on the tumor surface as well as evaluate the efficacy of anticancer drugs. furthermore,raman images reveal an inhomogeneous distribution of different compounds,especially proteins,lipids,microcalcifications,and their metabolic products,in cancerous breast tissues. information about these compounds may further our understanding of the mechanisms of breast cancer. © 2017 pin gao et al.
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آدرس
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department of breast surgery,first hospital of jilin university,changchun, China, department of breast surgery,first hospital of jilin university,changchun, China, department of breast surgery,first hospital of jilin university,changchun, China, department of breast surgery,first hospital of jilin university,changchun, China, department of breast surgery,second hospital of shandong university,jinan, China, state key laboratory for supramolecular structure and materials,jilin university,changchun, China, department of breast surgery,second hospital of shandong university,jinan,china,department of mechanical engineering,johns hopkins university,baltimore,md, United States, department of breast surgery,first hospital of jilin university,changchun, China
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Authors
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