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Fibre optic readout of microcantilever arrays for fast microorganism growth detection
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نویسنده
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maloney n. ,lukacs g. ,nugaeva n. ,grange w. ,ramseyer j.p. ,jensen j. ,hegner m.
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منبع
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journal of sensors - 2012 - دوره : 2012 - شماره : 0
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چکیده
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We present a fibre-optic-based device for the automated readout of microcantilever arrays for fast microorganism growth detection. we determined the ability of our device to track shifts in resonance frequency due to an increase in mass on the cantilever surface or changes in mechanical stiffness. the resonance frequency response of 7m thick agarose-functionalised cantilevers was tracked as humidity levels were varied revealing a mass responsivity of ~ 51 1 pg/hz. the resonance response of microcantilevers coated with aspergillus niger (a. niger) spores was monitored for >48h revealing a growth detection time of >4h. the growth of mycelium along the cantilevers surface is seen to result in an increase in resonance frequency due to the reinforcement of the cantilever structure. the use of our fibre optic detection technique allows data to be recorded continuously and faster than previously reported.
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آدرس
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school of physics,centre for research on adaptive nanostructures and nanodevices (crann),trinity college dublin, Ireland, school of physics,centre for research on adaptive nanostructures and nanodevices (crann),trinity college dublin, Ireland, toronto western hospital uhn,399 bathurst street, Canada, institut jacques monod,cnrs-université paris diderot, France, department of chemistry,university of basel,klingelbergstrasse 80, Switzerland, school of physics,centre for research on adaptive nanostructures and nanodevices (crann),trinity college dublin, Ireland, school of physics,centre for research on adaptive nanostructures and nanodevices (crann),trinity college dublin, Ireland
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Authors
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