Comparison of newly diagnosed ocular hypertension and open-angle glaucoma: Ocular variables,risk factors,and disease severity

Purpose. to describe the distribution of ocular variables,risk factors,and disease severity in newly diagnosed ocular hypertension (oh) or open-angle glaucoma (oag). methods. eligible subjects underwent a complete history and examination. adjusted odds ratios (ors) and 95% confidence intervals (cis) obtained from multiple logistic regression models were used to compare oag to oh and advanced to early/moderate oag. results. 405 subjects were enrolled: 292 (72.1%) with oag and 113 (27.9%) with oh. 51.7% had early,27.1% moderate,and 20.9% advanced oag. the or for oag versus oh was 8.19 (p < 0.0001) for disc notch,5.36 (p < 0.0001) for abnormal visual field,1.45 (p = 0.001) for worsening mean deviation,1.91 (p < 0.0001) for increased cupping,1.03 for increased age (p = 0.030),and 0.36 (p = 0.010) for smoking. conclusions. increased age was a risk for oag,and smoking decreased the risk of oag compared to oh. almost half of the oag subjects had moderate/advanced disease at diagnosis. © 2012 yvonne m. buys et al.