Comparison of macular thickness in diabetic macular edema using spectral-domain optical coherence tomography and time-domain optical coherence tomography

Purpose. to compare the macular thicknesses in diabetic macular edema (dme) measured with spectral-domain optical coherence tomography (sd-oct) and time-domain (td) oct. patients and methods. the average macular thicknesses of 50 eyes of 29 patients with dme were measured using sd-oct and td-oct. results. the mean macular thicknesses measured with td-oct and sd-oct were 401.5 ± 117.8 μm (mean ± sd) and 446.2 ± 123.5 μm,respectively. the macular thicknesses measured with the two devices were well correlated (pearson's product moment correlation,r = 0.977,p < 0.001). a significant correlation was found between the best-corrected visual acuity and the retinal thickness measured by td-oct and sd-oct (pearson's product moment correlation,td-oct,r = 0.34; p < 0.05; sd-oct,r = 0.32; p < 0.05). discussion. the mean macular thickness measured with sd-oct was about 45 μm thicker than that measured with td-oct. attention should be paid when comparing data obtained using different oct machines. © 2012 masashi kakinoki et al.