Is hyperopia an important risk factor for PACG in the dutch population? - A case control study

Objectives. to determine if hyperopia is a risk factor for primary angle-closure glaucoma (pacg) in the dutch population and to identify other biometrical parameters as risk factors for pacg including axial length (al),anterior chamber depth (acd),and k values. methods. the study population consisted of pacg patients that had undergone a laser peripheral iridotomy (lpi). the control group consisted of age- and gender-matched cataract patients. the main outcome was hyperopia (spherical equivalent ≥+0.5 dioptres) measured with iol master or autorefractor. refractive error,acd,al,and k values were tested with a mann-whitney u test and by logistic regression. results. 117 pacg patients and 234 controls were included (mean age = 80 years ± 3.6). the prevalence of hyperopia in patients and controls was 69.6% and 61.1%,respectively (fisher's test p = 0.076). mann-whitney u test showed no statistically significant relation with refractive error (p = 0.068) or k values (p = 0.607). in contrast,acd and al were statistically significant (p < 0.001). tested with logistic regression,only acd was a significant predictor of pacg (p < 0.001). conclusion. there was no statistically significant correlation between refractive error and pacg. acd was strongly correlated,though,with pacg,whereas al turned out to be a less significant risk factor. © 2013 saskia h. m. van romunde et al.