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Role of Intravitreal Antivascular Endothelial Growth Factor Injections for Choroidal Neovascularization due to Choroidal Osteoma
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نویسنده
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mansour a.m. ,arevalo j.f. ,al kahtani e. ,zegarra h. ,abboud e. ,anand r. ,ahmadieh h. ,sisk r.a. ,mirza s. ,tuncer s. ,navea tejerina a. ,mataix j. ,ascaso f.j. ,pulido j.s. ,guthoff r. ,goebel w. ,roh y.j. ,banker a.s. ,gentile r.c. ,martinez i.a. ,morris r. ,panday n. ,min p.j. ,mercé e. ,lai t.y.y. ,massoud v. ,ghazi n.g.
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منبع
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journal of ophthalmology - 2014 - دوره : 2014 - شماره : 0
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چکیده
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We treated 26 eyes of 25 young patients having a mean age of 30 years with intravitreal vascular endothelial growth factor (vegf) inhibitor for choroidal new vessel (cnv) formation overlying choroidal osteoma over a mean follow-up of 26 months. mean number of injections was 2.4 at 6 months,3.2 at 12 months,and 5.5 at 24 months. cnv was subfoveal in 14 eyes,juxtafoveal in 5,extrafoveal in 5,and peripapillary in 2. by paired comparison,mean decrease from baseline was 119.7 microns at 6 months (n = 15; p = 0. 001),105.3 microns at 1 year (n = 10; p = 0. 03),and 157.6 microns at 2 years (n = 7; p = 0. 08). bcva improved by 3.3 lines at 6 months after therapy (n = 26; p < 0. 001),2.8 lines (n = 20; p = 0. 01) at 1 year,and 3.1 lines (n = 13; p = 0. 049) at 2 years. we conclude that intravitreal anti-vegf injections improve vision in majority of eyes with cnv from choroidal osteoma. © 2014 ahmad m. mansour et al.
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آدرس
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departments of ophthalmology,american university of beirut,rafic hariri university hospital,p.o. box 113-6044, Lebanon, vitreoretinal division,king khaled eye specialist hospital, Saudi Arabia, vitreoretinal division,king khaled eye specialist hospital, Saudi Arabia, retina associates of cleveland,3401 enterprise parkway,beachwood, United States, vitreoretinal division,king khaled eye specialist hospital, Saudi Arabia, texas retina associates,university of texas southwestern medical center,dallas, United States, ophthalmic research center,shahid beheshti university of medical sciences,labbafinejad medical center, ایران, cincinnati eye institute,cincinnati, United States, birmingham midland eye centre,dudley road, United Kingdom, department of ophthalmology,istanbul faculty of medicine,istanbul university,a2 3 gayrettepe, Turkey, wilmer eye institute,johns hopkins university,baltimore, United States, fundación oftalmológica del mediterráneo,valencia, Spain, department of ophthalmology,lozano blesa university clinic hospital,university of zaragoza, Spain, mayo clinic,200 1st avenue south west rochester,minnesota, United States, university-eye hospital duesseldorf,moorenstraße 5, Germany, department of ophthalmology,university of wuerzburg, Germany, department of ophthalmology,st. mary's hospital,catholic university of korea, South Korea, banker's retina clinic and laser centre,5 subhash society,behind ishvar bhuvan,ahmedabad, India, department of ophthalmology,new york eye and ear infirmary,new york, United States, martinez center,avenida maría guerrero 144,leganés norte, Spain, department of retina and vitreous,aravind eye hospital and postgraduate institute of ophthalmology,avinashi road,coimbatore, India, mm joshi eye institute,gokul road,hosur,hubli, India, maryknoll medical center,4-12 daecheong-dong,jung-gu, South Korea, service d'ophtalmologie,chu dupuytren, France, department of ophthalmology and visual sciences, Hong Kong, departments of ophthalmology,american university of beirut,rafic hariri university hospital,p.o. box 113-6044, Lebanon, vitreoretinal division,king khaled eye specialist hospital, Saudi Arabia
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Authors
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