Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia

Purpose. to compare dry eye disease following smile versus fs-lasik. design. prospective,nonrandomised,observational study. patients. 90 patients undergoing refractive surgery for myopia were included. 47 eyes underwent smile and 43 eyes underwent fs-lasik. methods. evaluation of dry eye disease was conducted preoperatively and at 1,3,6,and 12 months postoperatively,using the salisbury eye evaluation questionnaire (seeq) and tbut. results. tbut reduced following smile at 1 and 3 months (p < 0.001) and at 1,3,and 6 months following fs-lasik (p < 0.001). tbut was greater following smile than fs-lasik at 3,6,and 12 months (p < 0.001,p < 0.001,and p = 0.009,resp.). seeq scores increased (greater symptoms) following smile at 1 month (p < 0.001) and 3 months (p = 0.003) and at 1,3,and 6 months following fs-lasik (p < 0.001). smile produced lower seeq scores (fewer symptoms) than fs-lasik at 1,3,and 6 months (p < 0.001). conclusion. smile produces less dry eye disease than fs-lasik at 6 months postoperatively but demonstrates similar degrees of dry eye disease at 12 months. © 2015 bingjie wang et al.