The Predictability of Preoperative Pilocarpine-Induced Lens Shift on the Outcomes of Accommodating Intraocular Lenses Implanted in Senile Cataract Patients

Purpose. to evaluate the predictability of lens shift induced by pilocarpine (l s p i l o) on the outcomes of accommodating intraocular lens (acc-iol) implantation. methods. twenty-four eyes of 24 senile cataract patients who underwent phacoemulsification and acc-iol implantation were enrolled. l s p i l o was evaluated with anterior segment optical coherence tomography (as-oct). at 3 months postoperatively,the best corrected distance visual acuities (bcdva),distance-corrected near visual acuities (dcnva),and subjective and objective accommodations were measured. iol shifts under accommodation stimulus (i o l s a c c) were evaluated with as-oct. results. the mean l s p i l o was 112.29 ± 30.72 μm. l s p i l o was not associated with any preoperative parameters. the mean i o l s a c c was 130.46 ± 42.71 μm. the mean subjective and objective accommodation were 1.54 ± 0.39 d and 1.27 ± 0.41 d,respectively. the mean postoperative bcdva and dcnva (log mar value) were 0.22 ± 0.11 and 0.24 ± 0.12,respectively. l s p i l o positively correlated with i o l s a c c (r = 0.541; p = 0.006),subjective accommodation (r = 0.412; p = 0.022),and objective accommodation (r = 0.466; p = 0.045),respectively. conclusion. l s p i l o is an independent preoperative parameter associated with the postoperative acc-iol mobility and pseudophakic accommodation. it may offer valuable information for ophthalmologists in determining the suitable candidates for acc-iol implantation. © 2016 jin li et al.