XEN Glaucoma Implant with Mitomycin C 1-Year Follow-Up: Result and Complications

Purpose. to evaluate gel microstent (xen,aquesys,inc) for treatment of primary open angle glaucoma (poag). methods. in this prospective interventional study,13 eyes with poag underwent xen implantation with subconjunctival mitomycin-c. of those eyes,3 were pseudophakic and 10 underwent simultaneous phacoemulsification and xen. patients had uncontrolled iop,had intolerance to therapy,or had maximal therapy but undergoing cataract extraction. follow-up visits included iop,number of medications,vision,and complications and lasted for 1 year. complete success was defined as iop reduction ≥20% from preoperative baseline at 1 year without any glaucoma medications while partial success as iop reduction of ≥20% at 1 year with medications. results. iop dropped from 16 ± 4 mmhg pre-op to 9 ± 5,11 ± 6,12 ± 5,12 ± 4,and 12 ± 3 mmhg at 1 week,1,3,6,and 12 months (p=0.004,0.026,0.034,0.01,and 0.01,wilcoxon signed ranks) consecutively. bcva (logmar) was 0.33 ± 0.34 and improved to 0.13 ± 0.11 at 1 year. mean number of medications dropped from 1.9 ± 1 preoperatively to 0.3 ± 0.49 (p=0.003) at 1 year. 42% of eyes achieved complete success and 66% qualified success. complications included choroidal detachment in 2 eyes,and implant extrusion in 1 eye,and 2 eyes underwent trabeculectomy. conclusion. xen implant is an effective surgical treatment for poag,with significant reduction in iop and glaucoma medications at 1 year follow-up. © 2017 ahmed galal et al.