Characterization of pure ductal carcinoma in situ on dynamic contrast-enhanced MR imaging: Do nonhigh grade and high grade show different imaging features?

To characterize imaging features of pure dcis on dynamic contrast-enhanced mr imaging (dce-mri),31 consecutive patients (37-81 years old,mean 56),including 2 grade i,16 grade ii,and 13 grade iii,were studied. mr images were reviewed retrospectively and the morphological appearances and kinetic features of breast lesions were categorized according to the acr bi-rads breast mri lexicon. dce-mri was a sensitive imaging modality in detecting pure dcis. mr imaging showed enhancing lesions in 29/31 (94%) cases. pure dcis appeared as mass type or non-mass lesions on mri with nearly equal frequency. the 29 mr detected lesions include 15 mass lesions (52%),and 14 lesions showing non-mass-like lesions (48%). for the mass lesions,the most frequent presentations were irregular shape (50%),irregular margin (50%) and heterogeneous enhancement (67%). for the non-mass-like lesions,the clumped internal enhancement pattern was the dominate feature,seen in 9/14 cases (64%). regarding enhancement kinetic curve,21/29 (78%) lesions showed suspicious malignant type kinetics. no significant difference was found in morphology (p . 05),tumor size (p = 0.21),and kinetic characteristics (p =. 38) between non-high grade (i+ii) and high-grade (iii) pure dcis. copyright © 2010 siwa chan et al.