Smoking,alcohol,and betel quid and oral cancer: A prospective cohort study

We aimed to investigate the association between smoking,alcoholic consumption,and betel quid chewing with oral cancer in a prospective manner. all male patients age ≥18 years who visited our clinic received an oral mucosa inspection. basic data including personal habits were also obtained. a multivariate logistic regression model was utilized to determine relevant risk factors for developing oral cavity cancer. a total of 10,657 participants were enrolled in this study. abnormal findings were found in 514 participants (4.8). three hundred forty-four participants received biopsy,and 230 patients were proven to have oral cancer. the results of multivariate logistic regression found that those who smoked,consumed alcohol,and chewed betel quid on a regular basis were most likely to develop cancer (odds ratio: 46.87,95 confidence interval: 31.84-69.00). therefore,habitual cigarette smokers,alcohol consumers,and betel quid chewers have a higher risk of contracting oral cancer and should receive oral screening regularly so potential oral cancer can be detected as early as possible. copyright © 2011 wen-jiun lin et al.