Influence of running and walking on hormonal regulators of appetite in women

Nine female runners and ten walkers completed a 60 min moderate-intensity (70 voax) run or walk,or 60 min rest in counterbalanced order. plasma concentrations of the orexogenic peptide ghrelin,anorexogenic peptides peptide yy (pyy),glucagon-like peptide-1 (glp-1),and appetite ratings were measured at 30 min interval for 120 min,followed by a free-choice meal. both orexogenic and anorexogenic peptides were elevated after running,but no changes were observed after walking. relative energy intake (adjusted for cost of exercise/rest) was negative in the meal following running (-194±206 kcal) versus walking (41±196 kcal) (p=0.015),although both were suppressed (p<0.05) compared to rest (299±308 and 284±121 kcal,resp.). the average rate of change in pyy and glp-1 over time predicted appetite in runners,but only the change in glp-1 predicted hunger (p=0.05) in walkers. results provide evidence that exercise-induced alterations in appetite are likely driven by complex changes in appetite-regulating hormones rather than change in a single gut peptide. © 2012 d. enette larson-meyer et al.