A case report on autoimmune polyendocrine syndrometype 1

Autoimmune polyendocrine syndrome type 1 (aps-1) is a rare autosomal recessive disorder characterized by autoimmune multiorgan dysfunction. the major components of aps type 1 are chronic mucocutaneous candidiasis,hypoparathyroidism and addison's disease. to establish this syndrome,at least two of these conditions have to be present. we report here one of such case,a 15-year old boy who presented with features of chronic mucocutaneous candidiasis,hypoparathyroidism,primary hypothyroidism,nail dystrophy and dental enamel hypoplasia that were consistent with aps-1.