Sulfonamides/co-trimaxazole resistant strains of escherichia coli causing urinary tract infection

Objective: to find out the frequency of sulfonamide resistant strains of escherichia coli (e.coli) causing urinary tract infection. material and methods: a cross sectional study was carried out to determine the resistant strains of e.coli to sulfonamide co-trimaxazole at the laboratories of the khyber teaching hospital,peshawar and pathology department,khyber medical college,peshawar from june 2008 to june 2010 which is catchment area for all of the peshawar town and its periphery. result: one hundred and thirty six patients presenting with urinary tract infection (uti) complaints were investigated for e.coli infections by collecting the urine specimens. urine culture and sensitivity (c/s) was done and the causative agents identified by routine microbiological examination and their sensitivity testing to co-trimaxazole were performed. out of 136 cases,121 (88.03%) cases were resistant to sulfonamide (co-trimaxazole) 15 cases (11.97%) were sensitive. conclusion: there is now a high incidence of sulfonamide (co-trimaxazole) resistant urinary tract infections.