Control of salmonella activity in rats by pulsed elf magnetic field (in vivo study)

In this work,the frequency of the magnetic impulses that interfere with the bioelectric signals generated during salmonella typhimurium (stm) cellular division is investigated. the experiment was expanded to in vivo study for the obtained data in which rats were infected with stm and then whole body were exposed to square magnetic pulses (smp) that caused inhibition to the microbial cellular growth. another group of animals was infected by previously inhibited bacteria with smp then the histological and molecular structures of the liver were investigated for all the animal groups. dielectric relaxation studies for the liver in the frequency range 100 khz - 4.5 mhz was used to determine molecular structure changes. the results indicated a highly significant inhibition of cellular growth for stm in addition to pronounced changes in the cellular morphology after the exposure of the micro-organism to the resonance frequency of 0.8 hz smp for 75 minutes. from the histological and dielectric relaxation measurements and results,it was indicated that the liver for animals infected by stm and then exposed to smp showed significant improvement in their health state as compared with infected and non exposed group. moreover,the liver for the animals infected with previously treated bacteria with smp showed highly significant decrease in cellular damage as compared with untreated bacteria. it was concluded that treatment of salmonella by 0.8 hz smp acts on the structure and biological activity of the bacteria and it is a promising methodology to control salmonella activity in vivo and in vitro applications.