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   The effect of NaF on the existence of ameloblasts and the change of tooth dimension  
   
نویسنده wahluyo s. ,nuraini p. ,rahayu r.p. ,ismiyatin k. ,handayani r. ,soetjipto professor at medical biochemistry departement
منبع journal of international dental and medical research - 2017 - دوره : 10 - شماره : 1 - صفحه:139 -144
چکیده    Ameloblasts cell which is very sensitive to the influence of internal and external factors. one external factor is the effect of fluoride elements that are able to affect the integrity of the ameloblasts cells and structure as well as the dimensions of the tooth enamel. this study seeks to analyze the effect of sodium fluoride exposure on the existence of tooth ameloblasts cells using indicators such as caspase-3,b-cel lymphoma 2 (bcl-2),the distance between ameloblasts cells,as well as changes in the size or teeth dimension. adult male healthy rats were used to experiment models,control (sterile distilled water treated),treatment group in to fluoride treated. the difference test on bcl-2 and caspase-3 between the control and the treatment groups showed different results (p < 0.05). similarly,the difference test on the distance between the ameloblasts cells as well as that on the dimensional change in both groups indicated significantly different results (p < 0.05). these results suggest that the induction of sodium fluoride showed the increase of caspase-3 protein expression,the decrease of bcl-2 expression,and the widening of the distance between ameloblasts cells,and the changes in the size or teeth dimension.
کلیدواژه Ameloblasts; Apoptosis; Sodium fluoride; Tooth dimension
آدرس paediatric dentistry departement,faculty of dentistry,universtas airlangga,jln.prof. moestopo 47,surabaya, Indonesia, paediatric dentistry departement,faculty of dentistry,universtas airlangga,jln.prof. moestopo 47,surabaya, Indonesia, oral patology departement,fakulty of dentistry,universtas airlangga,jln.prof moestopo 47,surabaya, Indonesia, conservative dentistry departement,faculty of dentistry,universtas airlangga,jln.prof. moestopo 47,surabaya, Indonesia, professor at medical biochemistry departement,faculty of medicine,universtas airlangga,jln.prof. moestopo 47,surabaya, Indonesia, faculty of medicine,universtas airlangga,jln.prof. moestopo 47,surabaya, Indonesia
 
     
   
Authors wahluyo ,nuraini ,rahayu ,ismiyatin ,handayani ,soetjipto
  
 
 

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