Correlation oral hairy leukoplakia and CD4+ counts in HIV/AIDS patients at Dr. soetomo hospital Surabaya,Indonesia 2014

Indonesia is a one of the countries in south east asia with a high prevalence of hiv/aids cases. oral hairy leukoplakia (ohl) is the one of the oral manifestations that often found in hiv/aids patient decreased cd4+ counts. ohl play an important role and it can be used as a clinical biomarker to determine the stage,progression,predict the onset of opportunistic diseases and a strong indicator of immunodeficiency condition. the aim of this study to investigate correlation ohl and cd4+ counts in hiv/aids patients at upipi rsud dr. soetomo surabaya 2014. this study was an analytic observational study with cross-sectional and total sampling method was conductet at upipi rsud dr. soetomo. the samples consisted of 88 hiv/aids patients from july-august 2014. diagnosed of ohl based on clinical appearance,the oral cavity of research subjects examined by oral medicine specialist. cd4+ counts obtained from patient's medical record. 88 hiv/aids patients were examined; there were 15 patients with ohl (17,05%). ohl was found to be significantly correlated to decreased of cd4+ counts < 200 cells/mm3 (p < 0.05). decreased of cd4+ counts affect the occurrence of ohl. ohl may be used as an alternative to cd4 count to diagnose the immunodeficiency hiv/aids patients.