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An overview of live attenuated recombinant pseudorabies viruses for use as novel vaccines
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نویسنده
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dong b. ,zarlenga d.s. ,ren x.
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منبع
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journal of immunology research - 2014 - دوره : 2014 - شماره : 0
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چکیده
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Pseudorabies virus (prv) is a double-stranded,dna-based swine virus with a genome approximating 150 kb in size. prv has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus propagation. recombinant prvs expressing both native and foreign antigens are able to stimulate immune responses. in this paper,we review the current status of live attenuated recombinant prvs and live prv-based vector vaccines with potential for controlling viral infections in animals. © 2014 bo dong et al.
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آدرس
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department of preventive veterinary medicine,college of veterinary medicine,northeast agricultural university,59 mucai street,xiangfang district, China, animal parasitic diseases laboratory,agricultural research service,beltsville, United States, department of preventive veterinary medicine,college of veterinary medicine,northeast agricultural university,59 mucai street,xiangfang district, China
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Authors
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