The role of the γ δ T cell in allergic diseases

The predominant distribution of γ δ t cells in the mucosal and epithelial tissues makes these unconventional lymphocytes the guards to contact external environment (like allergens) and to contribute to immune surveillance,as well as vanguards to participate in initiating mucosal inflammation. therefore,γ δ t cells have been considered to bridge the innate and adaptive immunity. the role these cells play in allergy seems to be complicated and meaningful,so it makes sense to review the characteristics and role of γ δ t cells in allergic diseases. © 2014 rui zheng and qintai yang.