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Bone-immune cell crosstalk: Bone diseases
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نویسنده
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mori g. ,d'amelio p. ,faccio r. ,brunetti g.
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منبع
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journal of immunology research - 2015 - دوره : 2015 - شماره : 0
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چکیده
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Bone diseases are associated with great morbidity; thus,the understanding of the mechanisms leading to their development represents a great challenge to improve bone health. recent reports suggest that a large number of molecules produced by immune cells affect bone cell activity. however,the mechanisms are incompletely understood. this review aims to shed new lights into the mechanisms of bone diseases involving immune cells. in particular,we focused our attention on the major pathogenic mechanism underlying periodontal disease,psoriatic arthritis,postmenopausal osteoporosis,glucocorticoid-induced osteoporosis,metastatic solid tumors,and multiple myeloma. copyright © 2015 giorgio mori et al.
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آدرس
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department of clinical and experimental medicine,university of foggia, Italy, department of medical science,section of gerontology and bone metabolism diseases,university of torino, Italy, department of orthopedics,washington university,school of medicine,st. louis, United States, department of basic medical sciences,neurosciences and sense organs,section of human anatomy and histology,university of bari, Italy
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Authors
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