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The novel functions of the PLC/PKC/PKD signaling axis in G protein-coupled receptor-mediated chemotaxis of neutrophils
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نویسنده
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xu x. ,jin t.
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منبع
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journal of immunology research - 2015 - دوره : 2015 - شماره : 0
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چکیده
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Chemotaxis,a directional cell migration guided by extracellular chemoattractant gradients,plays an essential role in the recruitment of neutrophils to sites of inflammation. chemotaxis is mediated by the g protein-coupled receptor (gpcr) signaling pathway. extracellular stimuli trigger activation of the plc/pkc/pkd signaling axis,which controls several signaling pathways. here,we concentrate on the novel functions of plc/pkc/pkd signaling in gpcr-mediated chemotaxis of neutrophils. © 2015 xuehua xu and tian jin.
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آدرس
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chemotaxis signal section,laboratory of immunogenetics,national institute of allergy and infectious diseases,national institutes of health,rockville, United States, chemotaxis signal section,laboratory of immunogenetics,national institute of allergy and infectious diseases,national institutes of health,rockville, United States
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Authors
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