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Immune regulation and antitumor effect of TIM-1
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نویسنده
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du p. ,xiong r. ,li x. ,jiang j.
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منبع
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journal of immunology research - 2016 - دوره : 2016 - شماره : 0
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چکیده
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T cells play an important role in antitumor immunity,and the t cell immunoglobulin domain and the mucin domain protein-1 (tim-1) on its surface,as a costimulatory molecule,has a strong regulatory effect on t cells. tim-1 can regulate and enhance type 1 immune response of tumor association. therefore,tim-1 costimulatory pathways may be a promising therapeutic target in future tumor immunotherapy. this review describes the immune regulation and antitumor effect of tim-1. © 2016 peng du et al.
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آدرس
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department of tumor biological treatment,third affiliated hospital,soochow university,changzhou,jiangsu,china,jiangsu engineering research center for tumor immunotherapy,changzhou,jiangsu,china,second people's hospital of gansu province,lanzhou,gansu, China, department of tumor biological treatment,third affiliated hospital,soochow university,changzhou,jiangsu,china,jiangsu engineering research center for tumor immunotherapy,changzhou,jiangsu,china,department of oncology,181st hospital of pla,guilin,guangxi, China, department of tumor biological treatment,third affiliated hospital,soochow university,changzhou,jiangsu,china,jiangsu engineering research center for tumor immunotherapy,changzhou,jiangsu, China, department of tumor biological treatment,third affiliated hospital,soochow university,changzhou,jiangsu,china,jiangsu engineering research center for tumor immunotherapy,changzhou,jiangsu, China
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Authors
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