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Advances in immunotherapy for glioblastoma multiforme
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نویسنده
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huang b. ,zhang h. ,gu l. ,ye b. ,jian z. ,stary c. ,xiong x.
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منبع
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journal of immunology research - 2017 - دوره : 2017 - شماره : 0
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چکیده
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Glioblastoma multiforme (gbm) is the most common primary malignant brain tumor in adults. patients with gbm have poor outcomes,even with the current gold-standard first-line treatment: maximal safe resection combined with radiotherapy and temozolomide chemotherapy. accumulating evidence suggests that advances in antigen-specific cancer vaccines and immune checkpoint blockade in other advanced tumors may provide an appealing promise for immunotherapy in glioma. the future of therapy for gbm will likely incorporate a combinatorial,personalized approach,including current conventional treatments,active immunotherapeutics,plus agents targeting immunosuppressive checkpoints. © copyright 2017 boyuan huang et al.
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آدرس
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department of neurosurgery,beijing electric hospital,state grid,beijing, China, department of neurosurgery,hubei provincial hospital of integrated chinese and western medicine,wuhan,hubei, China, central laboratory,renmin hospital of wuhan university,wuhan,hubei, China, department of hematology,renmin hospital of wuhan university,wuhan,hubei, China, department of neurosurgery,renmin hospital of wuhan university,wuhan,hubei, China, department of anesthesiology,perioperative and pain medicine,stanford university school of medicine,stanford,ca, United States, central laboratory,renmin hospital of wuhan university,wuhan,hubei,china,department of neurosurgery,renmin hospital of wuhan university,wuhan,hubei, China
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Authors
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