Vitamin D status and its relationship with metabolic markers in persons with obesity and type 2 diabetes in the UAE: A cross-sectional study

Aim. to report vitamin d status and its impact on metabolic parameters in people in the united arab emirates with obesity and type 2 diabetes (t2d).methodology. this cross-sectional study included 309 individuals with obesity and t2d who were randomly selected based on study criteria. serum concentrations of 25-hydroxy vitamin d (s-25(oh)d),calcium,phosphorus,parathyroid hormone,alkaline phosphatase,glycemic profile,and cardiometabolic parameters were assessed in fasting blood samples,and anthropometric measurements were recorded.results. vitamin d deficiency (s-25(oh)d < 50 nmol/l) was observed in 83.2% of the participants,with a mean s-25(oh)d of 33.8 ± 20.3 nmol/l. serum 25(oh)d correlated negatively (p<0.01) with body mass index,fat mass,waist circumference,parathyroid hormone,alkaline phosphatase,triglycerides,ldl-cholesterol,and apolipoprotein b and positively (p<0.01) with age and calcium concentration. waist circumference was the main predictor of s-25(oh)d status. there was no significant association between serum 25(oh)d and glycemic profile.conclusion. there is an overwhelming prevalence of vitamin d deficiency in our sample of the emirati population with obesity and t2d. association of s-25(oh)d with body mass index,waist circumference,fat mass,markers of calcium homeostasis and cardiometabolic parameters suggests a role of vitamin d in the development of cardiometabolic disease-related process. © 2014 amena sadiya et al.