Subjects with impaired fasting glucose: Evolution in a period of 6 years

Aim. to study the evolution of impaired fasting glucose (ifg),considering glucose and hba1c levels and risk factors associated,in a period of 6 years. methods. we studied 94 subjects with impaired fasting glucose (ifg) that were diagnosed in 2005 and followed up to 2012. glucose and hba1c levels were determined. a descriptive analysis of contingence charts was performed in order to study the evolution in the development of type-2 diabetes mellitus (t2dm). results. twenty-eight of ninety-four subjects became t2dm; 51/94 remained with ifg; and 20/94 presented normal fasting glucose. from the 28 diabetic subjects,9 had already developed diabetes and were under treatment with oral hypoglycemic agents; 5 were diagnosed with plasma glucose < 126 mg/dl,but with hba1c over 6.5%. in those who developed diabetes,15/28 had a family history of t2dm in first relative degree. also,diabetic subjects had a bmi significantly higher than nodiabetics (t test: p < 0.01). the individuals that in 2005 had the highest bmi are those who currently have diabetes. conclusion. the ifg constitutes a condition of high risk of developing t2dm in a few years,especially over 110 mg/dl and in obesity patients. © 2014 e. leiva et al.