Total Antioxidant Status in Type 2 Diabetic Patients in Palestine

The objective of this study was to compare the level of total antioxidant status (tas) in type 2 diabetic and normal palestinian subjects as well as the major factors influencing tas levels. a sample of convenience composed of 212 type 2 diabetic and 208 normal subjects above the age of 40 were recruited. only 9.8% of the subjects had normal body mass index (bmi) levels (<25),29% were overweight (≥25 to <30),and 61.2% were obese (≥30). the mean levels of tas were significantly higher in diabetic compared to control subjects (2.18 versus 1.84 mm trolox,p = 0.001) and in hypertensive subjects compared to subjects with normal blood pressure (bp). mean tas levels were higher in obese compared to nonobese subjects (2.12 versus 1.85 mm trolox,p = 0.001). mean tas levels were similarly higher in subjects with high fasting plasma glucose (fpg) compared to normal fpg (2.19 versus 1.90 mm trolox) and high hba1c (≥6.5%) compared to hba1c < 6.5% (2.14 versus 1.91 mm trolox). multivariate analysis revealed that only diabetic status (p = 0.032) and the level of education (p = 0.036) were significantly associated with tas. in conclusion diabetic patients had 18.5% increase in tas levels compared to control subjects. © 2015 akram t. kharroubi et al.