Wide-field megahertz OCT imaging of patients with diabetic retinopathy

Purpose. to evaluate the feasibility of wide-field megahertz (mhz) oct imaging in patients with diabetic retinopathy. methods. a consecutive series of 15 eyes of 15 patients with diagnosed diabetic retinopathy were included. all patients underwent megahertz oct imaging,a close clinical examination,slit lamp biomicroscopy,and funduscopic evaluation. to acquire densely sampled,wide-field volumetric datasets,an ophthalmic 1050 nm oct prototype system based on a fourier-domain mode-locked (fdml) laser source with 1.68 mhz a-scan rate was employed. results. we were able to obtain oct volume scans from all included 15 patients. acquisition time was 1.8 seconds. obtained volume datasets consisted of 2088 × 1044 a-scans of 60° of view. thus,reconstructed en face images had a resolution of 34.8 pixels per degree in x-axis and 17.4 pixels per degree. due to the densely sampled oct volume dataset,postprocessed customized cross-sectional b-frames through pathologic changes such as an individual microaneurysm or a retinal neovascularization could be imaged. conclusions. wide-field megahertz oct is feasible to successfully image patients with diabetic retinopathy at high scanning rates and a wide angle of view,providing information in all three axes. the megahertz oct is a useful tool to screen diabetic patients for diabetic retinopathy. © 2015 lukas reznicek et al.